fMRIDC - Database Search

My Account

Request List (Empty)

Sitemap

Contact Us

Denise C. Park, Robert C. Welsh, Christy Marshuetz, Angela H. Gutchess, Joseph Mikels, Thad A. Polk, Douglas C. Noll, Stephan F. Taylor.

Working Memory for Complex Scenes: Age Differences in Frontal and Hippocampal Activations

fMRIDC Accession Number: 2-2003-113QX
Journal of Cognitive Neursoscience 0 Dec ;15(8): p.1122-1134
PubMed ID: 14709231 (off-site link)

Study Meta-Data

Age differences in frontal and hippocampal activations in working memory were investigated during a maintenance and subsequent probe interval in an event-related fMRI design. Younger and older adults either viewed or maintained photographs of real-world scenes (extended visual or maintenance conditions) over a 4-sec interval before responding to a probe fragment from the studied picture. Behavioral accuracy was largely equivalent across age and conditions on the probe task, but underlying neural activations differed. Younger but not older adults showed increased left anterior hippocampal activations in the extended visual compared with the maintenance condition. On the subsequent probe interval, however, older adults showed more left and right inferior frontal activations than younger adults. The increased frontal activations at probe in older adults may have been compensatory for the decreased hippocampal activations during maintenance, but alternatively could have reflected the increased difficulty of the probe task for the older subjects. Thus, we demonstrate qualitatively different engagement of both frontal and hippocampal structures in older adults in a working memory task, despite behavioral equivalence.

Supplemental Information

Language: English
Country: United States
Has anatomical data
Has behavioral data
Has raw image data
Has high-res images
Has preprocessed image data

Comments on Working Memory for Complex Scenes: Age Differences in Frontal and Hippocampal Activations by interch on March 22, 2006 @14:48

[ Reply ]

Re: Reanalysis attempt by Petr on March 22, 2006 @14:49	[ Reply ]
This dataset was selected by a group of students engaged in analyses of the fMRIDC's dataset library using SPM5 and FSL tools, as part of an fMRI data analysis course at UC Davis. The 2-2003-113QX analysis log contains information that could be useful to others trying to utilize this dataset.

Web site design and development by
Paradigm Consulting Co.